Slc27a1 ELISA Kit for Mouse(Mus musculus) | EIAab.comSlc27a1 ELISA Kit for Mouse(Mus musculus)

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Slc27a1 (Gene name),

Long-chain fatty acid transport protein 1 (Protein name ), S27A1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Slc27a1(Fatp;Fatp1);

Protein name:

Long-chain fatty acid transport protein 1(FATP-1;Fatty acid transport protein 1);

Alternative:

Solute carrier family 27 member 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Self-associates. May function as an homodimer.

Function:

Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FatP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.

Subcellular Location:

Cell membrane Single-pass membrane protein Endomembrane system Single-pass membrane protein Cytoplasm Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes.

Protein Attributes:

Sequence length:

646

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

646:

KTRLQREGFD | PRQTSDRLFF | LDLKQGRYVP | LDERVHARIC | AGDFSL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00501

UniGene:

Mm.38165

String:

Q60714

SMR:

Q60714

KEGG:

mmu:26457

Uniprot:

Q60714

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ELISA Kit for Mouse FATP-1

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E12692r

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96T

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ELISA Kit for Mouse FATP-1

Cat.:

E12692m

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96T

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ELISA Kit for Mouse FATP-1

Cat.:

E12692h

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ELISA Kit for Mouse FATP-1

Cat.:

E12692b

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CLIA Kit for Mouse FATP-1

Cat.:

U12692h

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Packing:

96T

CLIA Kit for Mouse FATP-1

Cat.:

U12692r

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse FATP-1

Cat.:

U12692b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse FATP-1

Cat.:

U12692m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse FATP-1

Cat.:

P12692Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse FATP-1

Cat.:

P12692Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse FATP-1

Cat.:

P12692Rb-h

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40ug/0.2ml

Monoclonal Antibody for Mouse FATP-1

Protein for Mouse FATP-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein."
Schaffer J.E. , Lodish H.F.
Cell79:427-436(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Swiss.
2.

"Characterization of the murine fatty acid transport protein gene and its insulin response sequence."
Hui T.Y. , Frohnert B.I. , Smith A.J. , Schaffer J.E. , Bernlohr D.A.
J. Biol. Chem.273:27420-27429(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Retina.
4.

"Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport."
Stuhlsatz-Krouper S.M. , Bennett N.E. , Schaffer J.E.
J. Biol. Chem.273:28642-28650(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF SER-250
5.

"A family of fatty acid transporters conserved from mycobacterium to man."
Hirsch D. , Stahl A. , Lodish H.F.
Proc. Natl. Acad. Sci. U.S.A.95:8625-8629(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN FATTY ACID TRANSPORT;TISSUE SPECIFICITY
6.

"The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase."
Coe N.R. , Smith A.J. , Frohnert B.I. , Watkins P.A. , Bernlohr D.A.
J. Biol. Chem.274:36300-36304(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS AN ACYL-COA LIGASE;SUBCELLULAR LOCATION;MUTAGENESIS OF 249-THR--GLY-254
7.

"Molecular aspects of fatty acid transport: mutations in the IYTSGTTGXPK motif impair fatty acid transport protein function."
Stuhlsatz-Krouper S.M. , Bennett N.E. , Schaffer J.E.
Prostaglandins Leukot. Essent. Fatty Acids60:285-289(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF SER-250 AND THR-252
8.

"Membrane topology of the murine fatty acid transport protein 1."
Lewis S.E. , Listenberger L.L. , Ory D.S. , Schaffer J.E.
J. Biol. Chem.276:37042-37050(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TOPOLOGY
9.

"Oligomerization of the murine fatty acid transport protein 1."
Richards M.R. , Listenberger L.L. , Kelly A.A. , Lewis S.E. , Ory D.S. , Schaffer J.E.
J. Biol. Chem.278:10477-10483(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: OLIGOMERIZATION
10.

"Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes."
Stahl A. , Evans J.G. , Pattel S. , Hirsch D. , Lodish H.F.
Dev. Cell2:477-488(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"Characterization of the acyl-CoA synthetase activity of purified murine fatty acid transport protein 1."
Hall A.M. , Smith A.J. , Bernlohr D.A.
J. Biol. Chem.278:43008-43013(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS AN ACYL-COA LIGASE
12.

"Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle."
Kim J.K. , Gimeno R.E. , Higashimori T. , Kim H.J. , Choi H. , Punreddy S. , Mozell R.L. , Tan G. , Stricker-Krongrad A. , Hirsch D.J. , Fillmore J.J. , Liu Z.X. , Dong J. , Cline G. , Stahl A. , Lodish H.F. , Shulman G.I.
J. Clin. Invest.113:756-763(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
13.

"Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells."
Garcia-Martinez C. , Marotta M. , Moore-Carrasco R. , Guitart M. , Camps M. , Busquets S. , Montell E. , Gomez-Foix A.M.
Am. J. Physiol.288:C1264-C1272(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
14.

"Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast."
DiRusso C.C. , Li H. , Darwis D. , Watkins P.A. , Berger J. , Black P.N.
J. Biol. Chem.280:16829-16837(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION

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